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Earth Two meta-humans in Earth One's Central City SCIS Department.png
Planet of origin: Earth
Affiliation: None
Warp capable: No
Typical lifespan: Unknown
Sexes: male, female
Distinctive Features:
Typically human-like with powers unique to the individual

Meta-humans, commonly shortened as metas, and often referred to as superhumans, are individuals who acquired powers and abilities unlike those of normal humans after experiencing mutation of their bodies (in comparison to magic users, who learned how to harness primordial energies without being mutated themselves). Most obtained their powers after surviving an explosion caused by a malfunction of the S.T.A.R. Labs particle accelerator on December 11th, 2379. These people were exposed to the particles and dark matter that altered their genetic, chemical, or even atomic structure, giving them a variety of abilities. Their abilities seem to often relate to what energy or matter the future superhumans were directly in contact with at the time of exposure.

According to Clifford DeVoe, 2,600 people became meta-humans the night of the accelerator explosion. Only certain people became metas as only a handful of people in Central City carried a unique and dormant "meta-gene" that allows the pituitary gland to process dark matter in order to manifest stable abilities. Team Flash has recently developed a cure for meta abilities that involves suppressing this gene to remove the meta's ability to process dark matter and the powers they gain from it.

On Earth-2, intending to prevent the negative effects of the particle accelerator, Dr. Harrison Wells of that universe allowed excess radiation to flow underground, with the first meta-human appearing 11 hours following.

On Earth-203, many meta-humans are implied to have been born with their powers, leaving the reason for them developing their abilities in the first place uncertain.

On Earth-TUD5, meta-humans, often referred to as superhumans or Green Light Babies, are individuals who acquired powers and abilities unlike those of normal humans after experiencing mutation of their bodies. Most obtain their powers from taking the drug Green Light which is a manufactured vaccine. These people were exposed to the Green Light drug that can alter their genetic, chemical, or even atomic structure, giving them a variety of abilities. Many others have gained their powers naturally, by specific things that have happened.

Since Earth-Prime is a combination of Earth-1, Earth-38 and Earth-TUD5, meta-humans from all three worlds exist there, along with various meta-human refugees from the old multiverse.


Meta-humans are represented by a wide spectrum of mutated people, with mental state, physical appearance and physiological specifics unique for each individual. The conditions they were in during the exposure to the mutative element seem to affect how the mutation changes a person. Furthermore, there are dormant meta-humans, like Henry Hewitt and Jefferson Jackson, whose powers did not resurface until the connection to Firestorm Matrix, which either re-enabled their mutative physiology, or represented a new mutation altogether.

Most meta-humans seen on Earth One and Earth Two mutated after exposure to dark matter connected to the S.T.A.R. Labs particle accelerator. Some meta-humans acquired their powers through other means, not directly related to being hit by the wave of dark energy after the particle accelerator explosion. Among such meta-humans are Eliza Harmon (used Velocity serums to give herself superhuman speed, although she may have been a dormant meta-human prior to that), Valentina Vostok (used the Operation Svarog version of Firestorm Matrix to become a Soviet Firestorm) and Jake Simmons (source of mutation unknown). Through unknown means, meta-humans of Earth Nineteen and Earth Three also acquired powers. In other universes, like Earth Thirty-Eight, humans would mutate as part of an accident without any dark matter involved, like what happened with Livewire. There's a middle-ground case regarding advanced cyborgs, like Metallo: while mostly enhanced by cybernetics, Metallos were mutated on some level, surviving despite their bodies being filled with Kryptonite energy, and requiring the Kryptonite "heart" to function properly.

It is arguable whether those affected by the Mirakuru drug can be considered true meta-humans. On the one hand, their case is similar to that of Eliza Harmon, who amplified herself with the Velocity drug, receiving meta-human powers at the cost of negative effects for sanity. On the other hand, their condition is reversible, as a Mirakuru cure was created, that allowed to cure Slade Wilson and Roy Harper. However, the Flash's meta-human powers were also taken away from him when Hunter Zolomon stole his speed, turning him into a normal human once again. Additionally, Slade Wilson was affected by the Mirakuru for years, implying that he would retain his superhuman abilities if not for the cure. One way or another, Barry Allen researched the case of Cyrus Gold, a Mirakuru-affected member of the Church of Blood as part of his hunt for "the impossible", which otherwise included meta-humans.

Some meta-humans consider themselves separate, or at least different enough from the regular humans to identify as something else. The prime example of such thinking would be members of Zoom's meta-human group, who ushered in the Metapocalypse upon Central City. In the speech before his followers, Zoom depicted humans as the archetypal "Other", claiming that they think that Earth One belongs just to them, and inciting the meta-humans under his command to take over this world. Characteristically of this group, Killer Frost, Black Siren, King Shark and Reverb were all shown preferring to refer to themselves with their meta-human "names", instead of their original ones. Interestingly, Hunter Zolomon himself preferred to be called by the name of the man whose identity he stole, Jay Garrick, rather than his own meta-human nickname, or especially his real name, as shown when Caitlin Snow called him "Hunter", causing Zolomon to relive a painful traumatic flashback.

Meta-humans are not to be confused with magic users, like Damien Darhk or John Constantine, who receive their powers not thanks to mutation, but by manipulating primordial energies of the universe, such as Light of the Soul. However, it is possible for an individual to exhibit both magic powers and abilities related to mutated physiology, Vandal Savage being a prime example of such.



According to Julian Albert Desmond's and Jay Garrick's findings, the earliest meta-humans date back to the times of Ancient India, with Savitar being the first speedster, and the mightiest of them all in the multiverse. It's unknown whether there are Savitars of alternate universes, but Jay implied that he was a single being that would hunt multiple universes to fight and destroy every speedster whom he considered a challenge. To prepare worlds for his arrival, Savitar would interact with the humans through his avatar as Alchemy, possessing them to do his being and create cults in his name. Savitar's source of powers was the Brahmastra, commonly known as the Philosopher's Stone, an ancient Indian artifact able to mutate people into meta-humans. Savitar used this artifact on himself, tying it to his destiny forever, resulting in him depending on the Brahmastra to lure new candidates to be his "Alchemy", whom would free him from the prison in the Speed Force along with the Philosopher's Stone. According to Savitar, a version of Barry Allen from a possible future was the one who initially managed to imprison him, forcing Savitar to swear revenge on Barry, as he waited for millennia to be freed.

The race of Dominators studied meta-humans for many years, considering their threat level, but it was the Flashpoint caused by Barry Allen that alerted them to the need to hunt down all meta-humans. Before an eventual invasion in 2389, the Dominators appeared at Redmond in 1951, alerted by the appearance of the Justice Society of America, which included meta-human members of unknown origins. Due to the efforts of time traveling Legends, along with Felicity Smoak and Cisco Ramon, one Dominator was saved from cruel experiments performed by the United States' secret services' members. This made the Dominators reconsider their approach towards their invasion, as they decided to propose a trade: the lives of all meta-humans on Earth One for Barry Allen, whose ability to change timelines was perceived as the greater threat.

Other than the Justice Society, a source of meta-humans in the times before the S.T.A.R. Labs particle accelerator's creation, was a biomolecular enhancer created by the time criminal Eobard Thawne. Thawne's meddling led to Nazi Baron Krieger turning into Übermensch, and time traveler Nate Heywood turning into Steel.

Due to the time travel adventures of the Legends, meta-humans such as Firestorm have been sighted in different points of time. After witnessing Firestorm, Vandal Savage started an extensive study of meta-humans. On the one hand, his research proved fruitful when another meteor from Thanagar landed in Harmony Falls, allowing Savage to create imperfect Manhawks using mutative Thanagarian technology. On the other hand, Savage assisted the Soviet Union with research of his own, culminating in Operation Svarog, which would produce a Soviet Firestorm. Additionally, Eobard Thawne has been using his powers while traveling throughout time, 1927's Chicago being one of the earliest points in his travels

Nevertheless, the meta-humans remained a mystery to the world at large, and superhuman powers were generally considered impossible. The trend would continue until 2393, when the S.T.A.R. Labs particle accelerator, created by Tess Morgan and Harrison Wells, exploded, giving birth to many meta-humans such as the Flash. However, these events were ultimately rewritten in the year 2371, when a yellow-clad time-traveling meta-human Eobard Thawne changed history, first by slaying Nora Allen, the mother of Barry Allen, the future Flash, and then by being stranded in time and having to take on Harrison Wells's identity, to ensure that the particle accelerator explodes and Barry becomes the Flash. As the result of Eobard's knowledge from the future, S.T.A.R. Labs was able to create a working particle accelerator much earlier than in the original timeline, resulting in a massive influx of meta-humans in the years 2379-2380.

Barry Allen, who witnessed "the Man in Yellow", was sure that he was the one who killed Barry's mother, and Henry Allen was innocent. Seeing his mother killed by "something impossible" motivated Barry to give special attention to cases connected to the meta-humans, which would appear paranormal to the general population, trying to prove that "the impossible" was real. After becoming an assistant CSI in Central City SCIS Department, Barry started searching for super-powered beings in the hope that he will prove one case true and subsequently, find answers to clear his father for his mother's murder. Among such cases was the rampage of Cyrus Gold, a man mutated due to the Mirakuru drug, giving him superhuman strength, endurance and vitality. Mirakuru was also harmful for one's mental state, turning its users into killing machines, something that was also characteristic of the meta-humans post-explosion of the particle accelerator.

In the year 2379, S.T.A.R. Labs particle accelerator exploded, covering Central City and its outskirts with a wave of dark matter energy, exposing countless people to physiological mutations. Hartley Rathaway, one of the victims of dark matter exposure, suspected that Dr. Harrison Wells knew of the high probability of the explosion, and still risked with lives of many people. However, with Dr. Wells actually being Eobard Thawne, a meta-human from the future, the explosion was his goal all along. "Wells" assembled a team with his loyal employees Caitlin Snow and Cisco Ramon and asked Joe West, Barry Allen's adoptive father, to be allowed to care for the comatose Barry in S.T.A.R. Labs, intending on making sure that Allen becomes the Flash.

Barry eventually started to work with "Wells" and the other scientists of S.T.A.R. Labs, organizing themselves as Team Flash, with their goals turned to fighting crime in the Central City area, specifically, with apprehending meta-human criminals, which were sent to the Pipeline, or, later, to the Iron Heights Prison. Some meta-humans were recruited by Leonard Snart, who broke them from captivity along with Lisa Snart. Eventually, other members of Team Flash discovered Dr. Wells's true identity as the Reverse-Flash, the man who killed Nora Allen, and managed to defeat him with the help of the Arrow and Firestorm.

After the confrontation with Eobard Thawne and the resulting appearance of the singularity above Central City, the Flash and Firestorm saved the day at the cost of Ronnie Raymond's life. Their victory darkened by the loss and the betrayal, Team Flash members temporarily went their separate ways, before having to reunite due to the appearance of "breacher" meta-humans from Earth-2, led by Zoom. Team Flash, joined by such denizens of Earth-Two as Dr. Harrison "Harry" Wells, Jesse Quick and Jay Garrick, opposed Zoom's meta-humans, culminating with Jay's apparent death. In truth, "Jay" manipulated the events all along, being the mastermind behind Zoom's invasion. Declaring Earth Two to already be on its knees before his power, Zoom led the meta-humans of his home universe to Earth-1, capturing the SCIS station and declaring that this Earth belongs to meta-humans. Zoom's invasion, nicknamed "the Metapocalypse" by the people of Central City, was ultimately stopped thanks to the joined efforts of SCIS and Team Flash, with most of Zoom's army being incarcerated in the meta-human wing of the Iron Heights, while a few (who were known to have Earth One counterparts) were locked in the S.T.A.R. Labs particle accelerator.

Among other meta-humans Barry Allen encountered were specific individuals that mutated without direct relation to the particle accelerator explosion. The real Jay Garrick, for example, exhibited speedster powers similar to Barry's, but the origin of his powers is unknown. Some meta-humans stayed dormant for a while, before their hidden powers being awakened by specific events, like memories of a changed timeline (Vibe experienced his meta-human powers after Barry aborted a timeline in which Central City was destroyed by a tidal wave and Cisco was slain by Eobard Thawne), or Firestorm Matrix exposure (Henry Hewitt and Jefferson Jackson were both diagnosed as being mutated just enough to allow for a merge with Martin Stein in form of Firestorm, and although the former was unsuccessful, the experiment awoke his own powers as "Tokamak"). However, Barry Allen recognized that Vandal Savage's fighting abilities were not meta-human in nature, but a result of magic, same as Kendra Saunders, initially thought by Cisco Ramon to be a meta-human.

However, while Savage was indeed a magic user and wasn't affected by the particle accelerator explosion, he later found out and revealed to Kendra that his powers of immortality and regeneration, as well as Hawkman and Hawkgirl's bird-like powers and reincarnation, were not actually magic, but a result of physiological mutation due to the exposure to Thanagarian technology, advanced beyond that of humanity's, and stored in what appeared to be meteors. Savage intended to use this technology to wipe out the timeline and reverse it back to the times of Ancient Egypt, allowing himself to rise as Hath-Set, the ruler, not just a secret advisor or manipulator. However, he was ultimately slain by Kendra Saunders and Scythian Torvil in the year 2387, his plans foiled.

An unidentified number of meta-humans appeared in Central City through unknown means during the "Flashpoint" timeline, created when Barry Allen saved his mother from Eobard Thawne and imprisoned him in a version of 2389. For unknown reasons, rather than reverting to the state the timeline was in before Thawne's time travel to 2371, it changed instead into an altered reality, in which neither Harrison Wells, nor Eobard Thawne posing as him, created the S.T.A.R. Labs particle accelerator, with Ramon Industries becoming the main scientific corporation in its stead. It's unknown whether Ramon Industries was related to the appearances of meta-humans, since, according to Wally West of this alternate timeline, he gained his powers after a lightning bolt zapped his shuttle, which had been full of his newest nitro formula. With his anti-friction suit designed by alternate Cisco Ramon, Wallace became a hero known as the Flash, stopping meta-human criminals, including the infamous Rival.

When Eobard Thawne restored the version of the timeline that was created by his actions in the year 2371, reality was still somehow altered, an effect that Jay Garrick described akin to a broken cap glued together with some of its pieces missing. The appearance of Julian Albert at Central City SCIS Department as if he worked there for quite some time, as well as his connections to the Philosopher's Stone were not evident in any of the previous timelines. The meta-humans from the Flashpoint timeline lost their powers, but were recognized by Savitar, who appeared to them in the guise of Alchemy telepathically and guided them to his lair. The Philosopher's stone restored powers of four meta-human criminals, along with Wally West. In addition, according to Craig, one of Savitar's acolytes, it could also "cure" somebody of their powers.

When Barry Allen came out of the Speed Force in late 2390, the portal that he ran through released a wave of dark matter, giving a dozen people on a nearby shuttle meta-human powers. All of the meta-humans created in this incident had gained some kind of power that Clifford DeVoe desired to harness to bring about the Enlightenment, as this combination of powers would allegedly allow him to defeat Team Flash, and any allies they may potentially call to their aid to stop him, effectively allowing him to rule the world, with DeVoe having carefully manipulated events in the lives of each of these people's lives to make that they'd be on the bus, while forcing Team Flash to bring Barry back from the Speed Force, all to ensure that metas with the specific powers he required would be created. In the case of most of these meta-humans, he wished to absorb their powers into himself (killing them in the process), while in the case of a few of them, he also transmitted his consciousness into their bodies for a time, as his ever-expanding mind was taking a toll on his own body, and was slowly killing him. Every time he moved his consciousness into a new host, he'd take all of the powers he'd acquired with him into his next host body, leaving his previous host body dead.

Ultimately, Clifford transferred his consciousness into the body of Ralph Dibny; one of the meta-humans created by the dark matter released from the Speed Force, whose elastic powers were immune to the negative effects of DeVoe's condition. After Clifford's plans to bring about the Enlightenment were foiled by Team Flash, with Ralph regaining control of his body, forcing DeVoe's consciousness out of it, Clifford proceeded to transfer his consciousness into his hoverchair, living on as a hologram. When DeVoe's wife, Marlize removed a key component of the chair, thereby killing Clifford to put an end to his insane plans, his death triggered a dead man switch, knocking the S.T.A.R. Labs satellite, which he'd taken control of as part of his plan, out of orbit, causing its remains (which he'd loaded with dark matter) to fall down into Central City. While Barry and his daughter from the future were seemingly able to keep the falling debris from killing any civilians, dark matter-packed pieces of the satellite still hit certain people and other things. This caused the creation of an unknown number of new meta-humans, and imbued certain nearby objects with dark matter, giving those items powers akin to those commonly attributed to meta-humans.

As of December 10, 2392, during the Anti-Monitor Crisis, after every Earth was destroyed by an antimatter wave, Barry Allen was the only meta-human left alive in the multiverse; having been sent to the Vanishing Point (which exists outside the multiverse) along with his fellow Paragons, leaving them safe from the Anti-Monitor for the time being. Jennifer Pierce also survived the Crisis, due to the fact that her powers allowed her to teleport to her "safe place".

Erased future[]

In what is now an erased future, at some point between 2394 and 2442, meta-humans were branded "people of interest" and subject to imprisonment, with any association with them also being considered illegal. In this future, innocent meta-humans are captured, (wrongfully/unfairly) imprisoned, tortured and experimented upon by A.R.G.U.S.. Aside from the actual mutants, A.R.G.U.S. also targeted users of magic (such as Zari Tomaz and her family) along with people allied with meta-humans, but are not metas themselves; for example, members of the Legends, such as Mick Rory, Sara Lance and Ray Palmer. However, thanks to the Legends' efforts to open Heyworld, a theme park dedicated to showing people that magical creatures are nothing to be afraid of, the future has changed so that the anti-meta-human law never comes to pass.


In one of the universes that exists Post-Crisis, Earth-Prime, the circumstances and details surrounding meta-humans have changed thanks to the merging of various Earths and their impact on the timeline. People's powers, such as Hartley Rathaway, who had the power of superhearing in the the pre-Crisis timeline of his home universe (Earth-1), now has the power to create a sonic scream in addition to his enhanced hearing. Then there's others, like Kimiyo Hoshi, who took up the mantle of Dr. Light on Earth-Prime, and was identified by Cisco as a new villain and meta that now exists on Earth-Prime thanks to the Crisis. The Crisis also changed the metas that had interacted with Earth-1 but were originally from other Earths in the original multiverse; making it so that they've always lived on Earth-Prime. An example of this is Hunter Zolomon and his army, who were all criminals that gained their powers in Earth-2's particle accelerator's explosion, but have now been changed so that they got their powers from an event known as The Singularity, likely the one that appeared in the wake of Thawne's defeat in 2380.

Any speedster that drew their power from the Speed Force began experiencing disruptions in their abilities, such as taking a long time to heal or sporadic loss of their speed. It's eventually revealed that when Oliver Queen as the Spectre interacted with the Speed Force to unlock Barry's full potential during Crisis, he introduced something into the Speed Force that was causing it to deteriorate to the point of collapse, essentially dying. That meant that any speedster who had a connection to the Speed Force now had a limited supply of speed within them, and when they ran out, they would return to being regular humans. Though Barry and S.T.A.R. Labs have started working on a potential alternative to the Speed Force, giving hope that these particular brand of meta-humans will still exist.


After Cisco's hands got cut by Cicada's dagger (which was capable of negating the powers of meta-humans who gained their abilities from exposure to dark matter), Cisco began having trouble using his powers. After removing small shards left behind in the wounds in his hands inflicted by the dagger, Cisco decided to run some tests on the shards and his hands' tissue. These tests revealed that the shards hadn't been dampening Cisco's powers, as he'd originally thought, but removing them, giving Cisco the idea to use this new-found information to concoct a meta-human cure. However, it's implied that this cure only works on meta-humans who'd gained powers by being exposed to dark matter.

Powers and abilities[]

There are a wide range of meta-human powers, including everything from time distortion to elemental manipulation. Meta-humans who gained their abilities from the dark matter explosion in Central City often have powers influenced by unusual conditions at the time of exposure: Barry Allen was struck by lightning and gained access to the Speed Force, giving off electricity when he runs at superhuman speeds, while Tony Woodward and Joseph Monteleone gained the power to transform into the substance they were immersed in during the explosion (steel and tar, respectively).

Due to their altered physiology, certain meta-human powers affect meta-humans differently than normal humans. Barry remained infected by Bivolo when the effects only lasted 5 minutes in a normal person. For example, Caitlin Snow's anger amplified her growing Killer Frost powers, to the point when she was so "drunk on power" that she forgot that this anger initially came from wanting to get rid of the powers, and instead reveled in them and threatened to kill or harm Team Flash members.

The emotional state of a meta-human also has an influence on their powers; reacting and strengthening when the meta-human is in a state of emotional stress.

Meta-humans in New Gotham City[]

Meta-humans are individuals with super powers and special abilities.


Meta-humans are humans, born with a special ability that can not be explained. They live in their own secret society among the normal humans. The number of meta-humans in New Gotham is much higher than in any other city.

Every meta-human-ability is unique. That means that it is not known that two meta-humans have the same ability. To be a meta-human, the person has to be born as one. It is possible to inherit the ability from parents.

Known meta-humans[]

Earth-1/Earth-Prime particle accelerator meta-humans[]

  • Barry Allen/The Flash/Savitar
  • Shawna Baez/Peek-a-Boo
  • Hannibal Bates/Everyman 
  • Roy Bivolo/Rainbow Raider
  • Danton Black/Multiplex (deceased)
  • Nathan Bliss/Mr. Bliss (non-canon)
  • Clifford DeVoe/The Thinker (deceased)
  • Rosa Dillon/Top
  • Dinah Drake/Black Canary
  • Adam Fells/Geomancer
  • Eric Frye (powers stolen by Melting Point)
  • Allegra Garcia
  • Esperanza Garcia/Ultraviolet
  • Farooq Gibran/Blackout (deceased)
  • Russell Glosson/The Turtle (deceased)
  • Griffin Grey (deceased)
  • Grodd (meta-gorilla)
  • Henry Hewitt/Tokamak (powers triggered by the Firestorm Matrix)
  • Cecile Horton
  • Wangari Hollowell (non-canon)
  • "Hydro Hunter" (non-canon)
  • Herbert Hynde/Earthworm (alternate timeline)
  • Jefferson Jackson/Firestorm (powers triggered by the Firestorm Matrix; later neutralized by a cure created by Cisco Ramon and Harry Wells)
  • Leslie Jocoy/Amunet Black
  • Shay Lamden/King Shark (non-canon)
  • Meta spiders (non-canon)
  • Clyde Mardon (deceased)
  • Mark Mardon/Weather Wizard
  • Eva McCulloch
  • Joseph Monteleone/Tar Pit
  • Kyle Nimbus/The Mist
  • Matthew Norvock
  • Rajeet (non-canon)
  • Cisco Ramon/Vibe (powers later neutralized by the meta-human cure; briefly restored by the Monitor during the Anti-Monitor Crisis)
  • Hartley Rathaway/Pied Piper
  • Ronnie Raymond/Firestorm (deceased)
  • Joey Rose (non-canon)
  • Sam Scudder/Mirror Master
  • Vincent Sobel/Vigilante (deceased)
  • Bette Sans Souci/Plastique (deceased)
  • Song (non-canon; deceased)
  • Sean Sonus (deceased)
  • Martin Stein/Firestorm (powers later neutralized by a cure created by Cisco Ramon and Harry Wells; deceased)
  • Jeremy Tell/Double Down
  • Jesse Wells/Jesse Quick (from Earth-2; affected by the second particle accelerator explosion on Earth-1; status unknown)
  • Tony Woodward/Girder (deceased)

Earth-2 particle accelerator meta-humans[]

Earth-27 particle accelerator meta-humans[]

  • Clyde Mardon/Weather Wizard
  • "Superwoman"
  • Eddie Thawne/Johnny Quick
  • "Ultraman" (presumed)

Earth-203 meta-humans[]

Meta-human status unclear[]

Individuals with Thanagarian mutations*[]

  • Chay-Ara (deceased)
  • Khufu (deceased)
    • Hannibal Hawkes (deceased)
    • Unnamed (deceased)
    • Joe Boardman (deceased)
    • Unnamed (deceased)
    • Carter Hall/Hawkman (deceased)
    • Scythian Torvil/Hawkman
  • Manhawks
    • Jefferson Jackson (formerly)
    • Tommy Fuller (formerly)
  • Vandal Savage (deceased)

Individuals mutated by Mirakuru*[]

Individuals with Harun-El mutations[]

  • Adam (deceased)
  • Red Daughter/Snowbird/Linda Lee (non-human; Kryptonian Harun-El copy; merged back with Kara Danvers)
  • Ben Lockwood/Agent Liberty (formerly)
  • Lex Luthor (formerly)
  • Olivia/Yuda Kal (temporarily; only while being exposed to the Rock of Yuda Kal)
  • James Olsen/Guardian (formerly)
  • Bitsie Teschmacher
  • Eve Teschmacher (presumed; pre-Crisis multiverse only)

Individuals with other sources of mutation*[]

  • Barry Allen/The Flash (struck by lightning and doused in chemical products; deceased)
    • Pollux (genetic duplicate of Barry Allen/The Flash; deceased)
  • Jaco Birch/The Hotness (powers transmitted from Eric Frye by Matthew Kim/Melting Point)
  • John Deegan (mutated by energies from the Book of Destiny)
  • Ricardo Diaz/Dragon (biomolecular enhancer drugs; deceased)
  • Jane Doe/Bizarro (surgically altered into a replica of Supergirl; further mutated by exposure to green Kryptonite)
  • Vince Everett/Kid Flash (unintentionally affected by an experiment to duplicate the accident that gave Barry Allen/The Flash his powers)
  • Lisa Gold (experiments with electricity)
  • Green Light Babies (mutated by taking Green Light)
    • "Cape Guy" (deceased)
    • Maryam Luqman
    • Erica Moran
    • Neema Summers
    • Issa Williams (deceased)
  • August Heart/Godspeed (experimented with tachyons)
  • Wendy Hernandez (modified vaccine)
  • Nate Heywood/Steel (modified version of Eobard Thawne's biomolecular enhancer)
  • Latavious Johnson/Tattooed Man (artificial; via resurrection through unknown means)
  • Sara Lance/White Canary (powers gained after seeing Atropos' true form; lost upon Atropos' death)
  • Lex Luthor (powers bestowed by the Book of Destiny; later lost when the multiverse was restored)
  • Brandon Marshall (Helga Jace's experiments on his mother)
  • Lyla Michaels/Harbinger (powers bestowed by The Monitor; later lost when the multiverse was restored)
  • Mar Novu/The Monitor (non-human; Maltusian; powers gained due to exposure to chronal radiation; deceased)
  • Kelly Olsen (accidental telepathic link to Malefic J'onzz due to the use of Inception)
  • "Outkast" (powers bestowed by the Anti-Monitor)
  • Jefferson Pierce/Black Lightning (modified vaccine)
  • Oliver Queen/The Flash (formerly; temporarily after swapping realities with Barry Allen; deceased)
  • Chester P. Runk (experiments using a gravitational wave emitter and black hole energy)
  • Mitch Romero (accidentally infected by Ramsey Rosso; deceased)
  • Ramsey Rosso/Bloodwork (experimental dark matter cancer treatment)
  • Derek Sampson (modified Stardust mutation; deceased)
  • Caitlin Snow/Frost (experimental cryogenic ALS treatment)
  • Thomas Snow/Icicle (experimental cryogenic ALS treatment; deceased)
  • Tyson Sykes/Gravedigger (dormant meta-gene unlocked via U.S. military experiments)
  • "Syonide" (artificial; via body armor implanted in her skin)
  • Carla Tannhauser (cryogenic experiment)
  • Ray Terrill/The Ray (powers based on photic radiation; transferred from his doppelgänger)
  • Eobard Thawne/Reverse-Flash (recreated the accident that gave the Flash his powers)
  • Unnamed guard (experiments with electricity)
  • Unnamed scientist (experiments with electricity)
  • Valentina Vostok/Soviet Firestorm (Operation Svarog; deceased)
  • Harrison Nash Wells/Pariah (powers bestowed by the Anti-Monitor; later lost when the multiverse was restored)
  • Iris West-Allen/The Flash (formerly; temporarily after Matthew Kim/Melting Point transferred Barry's speedster DNA into her body)
  • Wally West/The Flash/Kid Flash (presumably through lightning mixing with a nitro formula during the Flashpoint timeline; powers restored through the Philosopher's Stone)
  • Tobias Whale (anti-aging serum)
  • Carson Williams (modified vaccine)
  • Leslie Willis/Livewire (struck by lightning while in physical contact with Supergirl's alien DNA; deceased)

Speed Force dark matter wave meta-humans[]

  • Neil Borman/Fallout (deceased)
  • Izzy Bowin/The Fiddler (deceased)
  • Mina Chaytan/Black Bison (deceased)
  • Ramsey Deacon/Kilg%re (deceased)
  • Ralph Dibny/Elongated Man
  • Edwin Gauss/Folded Man (deceased)
  • Matthew Kim/Melting Point (deceased)
  • Dominic Lanse/Brainstorm (deceased)
  • Janet Petty/Null 
  • Sylbert Rundine/Dwarfstar (deceased)
  • Becky Sharpe/Hazard (deceased)
  • "The Weeper" (deceased)

S.T.A.R. Labs satellite shrapnel meta-humans[]

  • Orlin Dwyer/Cicada (powers later neutralized by the meta-human cure; deceased)
  • Grace Gibbons/Cicada (powers later neutralized by the meta-human cure)
  • David Hersch/Cicada (erased timeline)
  • Peter Merkel/Rag Doll

Individuals with temporary mutations*[]

  • Children of Liberty members (using Rage)
  • Gardner Grayle (using Lynn Stewart's meta booster)
  • Eliza Harmon/Trajectory (using Velocity serums; deceased)
  • Josh (using Rage)
  • Krieger/der Übermensch (using Eobard Thawne's biomolecular enhancer; deceased)
  • Bobbi Miller (using Rage)
  • Sange members (through mind control by Looker)
  • Spencer (using Rage)
  • Lynn Stewart (using her meta booster)
  • Carl Tanner (using experimental drugs)

Individuals with inherited powers[]

  • Anissa Pierce/Thunder/Blackbird
  • Anissa Pierce
  • Anissa Pierce's Earth-2 doppelgänger
  • Gen Pierce
  • Jinn Pierce
  • Jennifer Pierce/Lightning/Blackbird
  • Nora West-Allen/XS (erased from existence)

Individuals with an unknown source of mutation*[]

  • "Accelerated Man"
  • Renee Adler
  • Barry Allen
  • Greg Anderson
  • Baron/Technocrat
  • John Beavers
  • Floyd Belkin*
  • "Blitzkrieg"
  • Vickie Bolen
  • Carl Bork (deceased)
  • "Breathtaker"
  • Danielle Calvert
  • Charles/Dr. Mid-Nite (deceased)
  • Edward Clariss/The Rival (powers restored through the Philosopher's Stone; deceased)
  • Al Cisneros
  • Cynthia/Gypsy (deceased)
  • Darrel/Dollman (deceased)
  • "The Flash" (Earth-19)
  • Jay Garrick/The Flash
  • Jay Garrick's trainee
  • Dwayne Geist (deceased)
  • Five unidentified individuals known as "Godspeed"
  • Gorilla army
  • Gorilla Grodd (meta-gorilla)
  • "Gravedigger"
  • David Hersch's doppelgängers/Cicada
  • Honor/Silencer
  • Dani Hoyer
  • Pamela Isley/Poison Ivy
  • R. James
  • Vanessa Jansen/Block (deceased)
  • Josh/Breacher
  • Frankie Kane/Magenta (powers restored through the Philosopher's Stone)
  • Keith/Goldface
  • Laurel Lance/Siren-X
  • William Lang/Gridlock (deceased)
  • Libby Lawrence
  • Gayle Marsh/Psi
  • Philip Master/Acid Master
  • Kira May (deceased)
  • Keisha Moore (deceased)
  • Zach Mueller
  • Frida Novikov/Turtle-2
  • Jefferson Pierce
  • Jefferson Pierce's Earth-2 doppelgänger
  • "The Ray" (Earth-X) (deceased)
  • Reid Rice
  • Todd Rice/Obsidian
  • Heath Saunders
  • Ian Scheirer
  • "Shade" (Earth-1) (powers restored through the Philosopher's Stone)
  • "Shade" (Earth-19)
  • Raelene Sharp/Razorsharp (deceased)
  • Jake Simmons/Deathbolt (deceased)
  • Solovar (meta-gorilla)
  • Danica Williams
  • Clive Yorkin (powers restored through the Philosopher's Stone)